Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome

Article ID	Journal	Published Year	Pages	File Type
5961432	Heart Rhythm	2013	6 Pages	PDF

Abstract

Our findings suggest that mutations with a wider variation in QTc duration are associated with increased risk of cardiac events. These findings appear to be genotype-specific, with a pronounced effect among patients with the long QT syndrome type 1 genotype.

Keywords

LQTS QTc LQT2 long QT syndrome type 2 electrocardiogram/electrocardiographic ECG Long QT syndrome corrected QT interval confidence interval Sudden cardiac death hazard ratio Single nucleotide polymorphism SNP

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

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Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome

Authors

Andrew MD, Arthur J. MD, Coeli M. PhD, Alon MD, Scott MS, Wojciech MD, PhD, Jennifer L. MS, Emanuela H. MD, Michael J. MD, PhD, Jesaia MD, Elizabeth S. MD, Pyotr G. MD, PhD, Ming MD, Wataru MD, PhD, Jeffrey A. MD, G. MD, Arthur A.M. MD, PhD, Li MD,