| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5961631 | Heart Rhythm | 2010 | 8 Pages |
Abstract
Pirfenidone decreased total and nonscar fibrosis in a rat MI model, which correlated with decreased infarct scar, improved LV function, and decreased VT susceptibility. Directly targeting post-MI fibrotic substrates may have a role in limiting infarct-dense scar, improving LV function, and reducing VT vulnerability.
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Authors
Duy T. MD, Chunhua MD, PhD, Emily BS, Gregory M. MD, Jeffrey E. MD,