Article ID Journal Published Year Pages File Type
59618 Chinese Journal of Catalysis 2014 4 Pages PDF
Abstract

A series of amphiphilic proline-derived mercapto imidazole organic catalysts were synthesized and shown to be very effective with an acid cocatalyst for the asymmetric Michael addition reaction of ketones to nitroolefins with high diastereoselectivity (up to 99:1) and execellent enantioselectivity (up to 96%) using water as solvent.

Graphical AbstractMichael addition was catalyzed by a new amphiphilic proline]derived mercapto imidazole organic catalyst using water as solvent with high diastereoselectivity (99:1 d.r.) and execellent enantioselectivity (96% ee).Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
Authors
, , , , , ,