Rh(III)-catalyzed oxidative amidation of aldehydes: An efficient route to N-pyridinamides and imides

A novel Rh(III)-catalyzed direct amidation of aldehydes featuring Ag2CO3 as the oxidant is described. This selective procedure provides a variety of N-pyridinamides and imide derivatives in good yields.

Graphical AbstractA novel Rh(III)-catalyzed direct amidation of aldehydes is described, featuring Ag2CO3 as the oxidant. Many types of amide derivatives were prepared: N-pyridinamides, N-isoquinolinamides, and imides.Figure optionsDownload full-size imageDownload as PowerPoint slide