Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5961937 | Heart Rhythm | 2010 | 8 Pages |
Abstract
Occurrence of compound and double heterozygotes in ARVC/D index cases is particularly relevant to mutation screening strategy and to genetic counseling. Even if multiple-mutation carriers show a wide variability in clinical expression, the extent of the disease is higher compared to that in single-mutation carriers.
Keywords
ARVC/DRPDDHPLCArrhythmiaECGelectrocardiogramRight ventricularVentricular tachycardiagene mutationsICDSudden deathcell adhesion moleculesArrhythmogenic right ventricular cardiomyopathy/dysplasiaarrhythmogenic cardiomyopathyImplantable cardioverter-defibrillatorDenaturing high-performance liquid chromatography
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Authors
Barbara MD, PhD, Andrea MD, Giorgia BSc, PhD, Cristina MD, PhD, Alessandra BSc, PhD, Gessica BSc, PhD, Marzia BSc, PhD, Ilaria MD, PhD, Elisa MD, PhD, Alexandros MD, Martina Perazzolo MD, PhD, Jeffry A. MD, PhD, Gaetano MD, Gian Antonio BSc, PhD,