Poly(4-vinylpyridinium) perchlorate as an efficient and recyclable catalyst for the synthesis of biscoumarins and bisindoles

Poly(4-vinylpyridinium) perchlorate has been used as an efficient solid acid catalyst for the synthesis of 3,3'-(arylmethylene)bis(4-hydroxycoumarins) and bis(indolyl)methanes, with the products being formed in excellent yields over very short reaction times under mild and environmentally friendly conditions. This catalyst can be reused several times without any appreciable loss in its activity.

Graphical AbstractA mild, simple, and efficient procedure has been developed for the synthesis of 3,3'-(arylmethylene)-bis-(4-hydroxy coumarins) and bis(indolyl)methanes using poly(4-vinylpyridinium) perchlorate [P(4-VPH)ClO4] as an efficient heterogeneous catalyst.Figure optionsDownload full-size imageDownload as PowerPoint slide