Cu-doped ZnO nanocrystalline powder catalyzed one-pot synthesis of fully substituted new indeno[1,2-b]pyridines at room temperature by a multi-component reaction

Cu doped ZnO nanocrystalline powder (10 mol%) has been found to be an efficient catalyst for the one-pot multi-component synthesis of fully substituted new indeno[1,2-b]pyridines through a combination of 1,3-indandione, propiophenone or acetophenone derivatives, aromatic aldehydes, and ammonium acetate in ethanol/H2O at room temperature. The methodology is mild, efficient and high to excellent yielding.

Graphical AbstractWe synthesized fully substituted new indeno[1,2-b]pyridines through a multi-component reaction of 1,3-indandione, aromatic aldehydes, propiophenone or acetophenone derivatives and ammonium acetate in the presence of Cu-doped ZnO nanocrystalline powder (10 mol%) in ethanol/H2O at room temperature.Figure optionsDownload full-size imageDownload as PowerPoint slide