Concomitant takotsubo cardiomyopathy with PRES syndrome: A coincidence or a real heart-brain connection?

Takotsubo cardiomyopathy is a clinical entity characterized by reversible ventricular dysfunction in the absence of obstructive coronary artery disease. Posterior reversible encephalopathy syndrome is another rare clinical syndrome characterized by reversible neurological symptoms. Concomitant occurrence is increasingly reported leading to credence to hypothesis of “heart-brain connection”. We present a case of a 60-year-old female admitted for neurological symptoms who developed takotsubo cardiomyopathy within 24 h of admission.