Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5987109 | The Journal of Heart and Lung Transplantation | 2016 | 10 Pages |
Abstract
Pulmonary vascular Egr-1 expression is significantly increased in patients with PAH, appears specifically associated with neointimal-type vascular remodeling, and correlates with disease progression. These data translate the critical role of Egr-1 in the development of experimental PAH to human pulmonary vascular disease forms.
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Authors
Diederik E. MD, Michael G. MD, PhD, Beatrijs MD, PhD, Marinus A.J. MD, PhD, Hannie MD, PhD, Marilyne MD, PhD, Rolf M.F. MD, PhD,