Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5987189 | The Journal of Heart and Lung Transplantation | 2016 | 26 Pages |
Abstract
The genetic spectrum of familial DCM patients undergoing HTx is heterogeneous and involves multiple genes. NGS technology plus detailed familial studies allow identification of causative mutations in the vast majority of familial DCM cases. Detailed familial studies remain critical to determine the pathogenicity of underlying genetic defects in a substantial number of cases.
Keywords
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Authors
Sofia MD, Maria J. MD, PhD, Juan Ramón MD, PhD, Alfonso MD, Clara MD, Iria BSc, Laura PhD, Jose Javier MD, Carlos MD, PhD, Javier MD, PhD, Domingo MD, PhD, Enrique PhD, Lorenzo MD, PhD, Luis MD, PhD, Pablo MD, PhD,