Article ID Journal Published Year Pages File Type
5987299 The Journal of Heart and Lung Transplantation 2015 11 Pages PDF
Abstract
Endothelin-1 downregulates canonical BMPR2 signaling. This is related to decreased BMPR2 and increased anti-BMP gremlin expression associated with increased activation of p38MAPK and results in PA-SMC proliferation.
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Related Topics
Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
Endothelin-Bone morphogenetic protein type 2 receptor interaction induces pulmonary artery smooth muscle cell hyperplasia in pulmonary arterial hypertension
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