Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5987307 | The Journal of Heart and Lung Transplantation | 2014 | 11 Pages |
Abstract
Pump exchange or death due to pump thrombosis increased during 2011 and 2012, but the magnitude of the increase remained relatively small. Survival remains high (80% at 1 year) with the HMII LVAD. Risk factor analysis suggests that a number of patient-related factors contribute to the risk of thrombosis. Markedly elevated lactate dehydrogenase in the first month is a predictor of pump thrombosis. This analysis could not examine the potential role of technical factors during implant, such as sub-optimal pump or graft positioning, changes in patient management paradigms with pump speed settings, improved recognition and change in the threshold for pump exchange, or design or production changes with the pump, as contributors to the risk of pump thrombosis.
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Authors
James K. MD, David C. PhD, Robert L. MD, Francis D. MD, Susan L. MPH, Lynne W. MD, Michael A. MD, Daniel L. MD, Scott C. MD, Carmelo A. MD, J.T. MD, Sean MD, J. MD, Marissa A. DVM, MPH,