| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5987440 | The Journal of Heart and Lung Transplantation | 2010 | 7 Pages |
Abstract
Myocardial β-AR signaling can be restored to nearly normal after continuous-flow LVAD support. This is similar to previous data for volume-displacement pulsatile LVADs. Decreased GRK2 activity is an important mechanism and indicates that normalization of the neurohormonal milieu associated with HF is similar between continuous-flow and pulsatile LVADs. This may have important implications for myocardial recovery.
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Authors
Shahab A. MD, Karen M. PhD, Ricky PhD, Michelle L. BS, Tracy B. RN, MSN, Savitri E. MD, Allen S. MD, Jai MD, PhD, Valluvan MD,