Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
599218 | Colloids and Surfaces B: Biointerfaces | 2015 | 17 Pages |
Abstract
- Targeting ligands enhance internalization of polymeric nanoparticles in cancer cells.
- TAT is exposed by shield/deshielding mechanism to avoid non-specific binding.
- Tumor pH actives ligand-mediated delivery for tumor targeting.
- Tumor pH triggers charge conversion to tumor cell uptake.
- Polymeric nanoparticles have the potential to overcome resistance.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Lu Sun, Qinjie Wu, Feng Peng, Lei Liu, Changyang Gong,