| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 599424 | Colloids and Surfaces B: Biointerfaces | 2015 | 34 Pages |
Abstract
Injection of cholesterol-free immunoliposomes targeted against apolipoprotein B-100 improves lipid profile in tyloxapol-induced hyperlipidemic mice. Immunoliposomes can interact with serum lipoproteins via lipid exchange between the vesicles, and direct capture of atherogenic lipoproteins via apoB-100 monoclonal antibodies on the liposome surface. Resulting liposome-lipoprotein complexes will be efficiently cleared from serum by liver.
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Physical Sciences and Engineering
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Colloid and Surface Chemistry
Authors
Amirhossein Sahebkar, Ali Badiee, Mahdi Hatamipour, Majid Ghayour-Mobarhan, Mahmoud Reza Jaafari,