Article ID Journal Published Year Pages File Type
599436 Colloids and Surfaces B: Biointerfaces 2015 8 Pages PDF
Abstract

- There is a simple mechanism of adsorption-induced conformational changes of proteins.
- The unfolding pathway of a protein remains similar upon adsorption on silica.
- The folding stability is significantly reduced in the adsorbed state.
- The results are based on both pressure and temperature induced unfolding.
Keywords
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
Preview
Secondary structure and folding stability of proteins adsorbed on silica particles - Pressure versus temperature denaturation
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