Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
599492 | Colloids and Surfaces B: Biointerfaces | 2014 | 10 Pages |
Abstract
- Redox and pH sensitive PAMAM-SS-PEG conjugates were synthesized by a simple process.
- Conjugates exhibited excellent stability and effectively diminished uptake by RES.
- Drug release from the conjugates was followed a reduction and pH-triggered pattern.
- DOX-loaded conjugates showed significant cytotoxicity against B16 and A549 cells.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Wen Hu, Liang Cheng, Lifang Cheng, Meng Zheng, Qifu Lei, Ziyang Hu, Ming Xu, Lipeng Qiu, Dawei Chen,