| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 599504 | Colloids and Surfaces B: Biointerfaces | 2014 | 19 Pages |
Abstract
- Many hydrophilic small molecule drugs undergo suboptimal encapsulation and delivery.
- We review liposomal loading of hydrophilic small molecule drugs.
- Lipid composition, drug/lipid ratio, charge and loading method affect encapsulation.
- Liposomal targeted and triggered delivery enhance efficacy of hydrophilic drugs.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Josimar Oliveira Eloy, Marina Claro de Souza, Raquel Petrilli, Juliana Palma Abriata Barcellos, Robert J. Lee, Juliana Maldonado Marchetti,