| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 599590 | Colloids and Surfaces B: Biointerfaces | 2015 | 8 Pages |
Abstract
- A novel DNA-condensation strategy was developed to study DNA adsorption on amino-modified silica-coated magnetic nanoparticles (ASMNPs).
- Condensation agents (e.g., PEG/NaCl) can induce DNA conformation change and prompt DNA adsorption on ASMNPs.
- Maximum adsorption capacity of ASMNPs for condensed DNA is higher than that for elongated DNA.
- Practical application for plasmid DNA isolation confirmed the reliability of this method.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Zhi Shan, Youjun Jiang, Mengyu Guo, J. Craig Bennett, Xianghai Li, Hefeng Tian, Ken Oakes, Xu Zhang, Yi Zhou, Qianming Huang, Huaping Chen,