Article ID Journal Published Year Pages File Type
599691 Colloids and Surfaces B: Biointerfaces 2014 9 Pages PDF
Abstract

- The composition of resveratrol (RES) nanoparticles (NPs) was optimized by Box-Behknken design.
- The optimal NPs had average diameter of 135 nm and an encapsulation efficiency of 99.8%.
- Trehalose (>15%) was the most effective sugar for NPs stabilization during freeze drying.
- The blank NPs were not cytotoxic at lower concentrations (<600 µg/mL).
- Cell viability was significantly decreased at higher native RES concentrations (>50 µM).
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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