Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
599783 | Colloids and Surfaces B: Biointerfaces | 2013 | 6 Pages |
Abstract
- Increases in the polyols' hydroxyl groups leads to an increase in tablet strength
- Increases in the polyols' hydroxyl groups maybe responsible for the decrease in the drug release rates.
- Maltitol was resilient in the presence of ethanol (5-40% v/v) at pH 1.2
- Ehanol concentrations as high as 40% (v/v), did not substantially alter drug release properties of theophylline from maltitol matrix tablets.
- Of all polyols studied, maltitol was the most resilient
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Kofi Asare-Addo, Barbara R. Conway, Mohamed J. Hajamohaideen, Waseem Kaialy, Ali Nokhodchi, Hassan Larhrib,