Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
599915 | Colloids and Surfaces B: Biointerfaces | 2014 | 9 Pages |
Abstract
- Amoitone B, a novel synthesized Cytosporone B derivative, is a promising anticancer drug.
- Amoitone B nanocrystals markedly enhanced cytotoxicity to BGC-823, SW620, HepG2 and H460 cancer cells.
- Amoitone B nanocrystals induce G1 cycle arrest and markedly improve the apoptosis of human gastric cancer BGC-823 cell line.
- Tissue distribution study demonstrated that Amoitone B nanocrystals had a higher distribution in liver and lung.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Leilei Hao, Jingjing Luan, Dianrui Zhang, Caiyun Li, Hejian Guo, Lisi Qi, Xinquan Liu, Tingting Li, Qiang Zhang,