Article ID Journal Published Year Pages File Type
599915 Colloids and Surfaces B: Biointerfaces 2014 9 Pages PDF
Abstract

- Amoitone B, a novel synthesized Cytosporone B derivative, is a promising anticancer drug.
- Amoitone B nanocrystals markedly enhanced cytotoxicity to BGC-823, SW620, HepG2 and H460 cancer cells.
- Amoitone B nanocrystals induce G1 cycle arrest and markedly improve the apoptosis of human gastric cancer BGC-823 cell line.
- Tissue distribution study demonstrated that Amoitone B nanocrystals had a higher distribution in liver and lung.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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