Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
599998 | Colloids and Surfaces B: Biointerfaces | 2014 | 8 Pages |
Abstract
- Analysis of solid-phase PEGylation using immobilized protein cages by QCM.
- The percentage of surface covered with PEG was controlled by PEGylation conditions.
- Immobilized protein cages provide a spatially restricted reaction field for PEGylation.
- A mechanism was proposed to illustrate the solid-phase PEGylation of protein cages.
- The protein cage surface covered with PEG alters the interaction with other proteins.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Koichiro Uto, Kazuya Yamamoto, Kenji Iwahori, Takao Aoyagi, Ichiro Yamashita,