Article ID Journal Published Year Pages File Type
6000815 Thrombosis Research 2015 4 Pages PDF
Abstract

•AGEs increased PAR-2 levels in tubular cells.•Factor Xa increased ROS and MCP-1 mRNA levels in tubular cells.•AGEs potentiated the effects of Xa on tubular cells.•Rivaroxaban or an antagonist of PAR-2 blocked the harmful actions of Xa.

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