Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6001162 | Thrombosis Research | 2015 | 8 Pages |
Abstract
Inhaled NO can suppress elevated PAI-1 expression in rats with ALI induced by endotoxin. Although exposure to high-concentration oxygen prolongs the duration of PAI-1 mRNA overexpression in ALI, inhaled NO can reduce this effect and alleviate both fibrin deposition and lung injury.
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Authors
Yang Chen, Zhu-Jin Lu, Yi Yang, Guo-Ping Lu, Wei-Ming Chen, Ling-En Zhang,