Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6001290 | Thrombosis Research | 2015 | 6 Pages |
Abstract
In logistic regression analysis, only ÎTAT (optimal cut-off > 178% from baseline demonstrated a significant risk increase for VTE/death (odds ratio 3.76; 95% confidence interval 1.46-9.68; p = 0.006). In conclusion, the concept of testing coagulation activation parameters may also be transferred to VTE patients at the end of DOAC therapy. For patients with an increase of TAT levels within 4 weeks after treatment discontinuation (> 178% from baseline) is associated with an increased risk for VTE recurrence or death at 12 months.
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Authors
Jan Beyer-Westendorf, Siegmund Gehrisch, Thoralf Stange, Luise Tittl, Gabriele Siegert, Norbert Weiss,