Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6001352 | Thrombosis Research | 2015 | 7 Pages |
Abstract
α-FXIIa enhances fibrinolysis in the presence of plasminogen, irrespective of whether tPA was present during clot formation or was added afterwards to initiate fibrinolysis. We postulate that FXIIa first strengthens the clot structure during clot formation and thereafter contributes towards fibrinolysis.
Keywords
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Authors
Joke Konings, Lisa R. Hoving, Robert S. Ariëns, Emma L. Hethershaw, Marisa Ninivaggi, Lewis J. Hardy, Bas de Laat, Hugo ten Cate, Helen Philippou, José W.P. Govers-Riemslag,