| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6001549 | Thrombosis Research | 2015 | 24 Pages |
Abstract
The platelet count in CHC is significantly associated with fibrosis, TPO level, IPF, and spleen size. Our findings challenge the proposed mechanism of decreased TPO levels or decreased bone marrow production of platelets as a cause of thrombocytopenia in CHC. Future studies focusing on the effects of fibrosis and splenomegaly on platelets may shed more light on the pathophysiology of thrombocytopenia in patients with CHC.
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Authors
Michele M. Tana, Xiongce Zhao, Alyson Bradshaw, Mi Sun Moon, Sandy Page, Tiffany Turner, Elenita Rivera, David E. Kleiner, Theo Heller,