Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6002232 | Thrombosis Research | 2014 | 7 Pages |
Abstract
With the present two-step approach assay nine out of 23 (39%) patients affected with AVWS resulted positive for anti-VWF autoantibodies. This ELISA assay might be used as an additional confirmation tool in the diagnostic procedure in patients affected by AVWS or in the follow-up of congenital and acquired patients exposed to replacement therapy.
Keywords
FVIII:CVWF:CBfactor VIII coagulant activityEssential thrombocytemiaMGUSAVWSCLLvWFautoantibodiesPBSBSAVWF:AgVWF:RCobovine serum albuminvon Willebrand factor antigenstandard deviationELISAEnzyme-linked immunosorbent assayRoom temperatureacquired von Willebrand syndromenormalization factorVon Willebrand factorphosphate buffer salineChronic lymphocytic leukemiaSpecificityoptical densitymonoclonal gammopathy of undetermined significance
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Authors
Franca Franchi, Eugenia Biguzzi, Francesca Stufano, Simona M. Siboni, Luciano Baronciani, Flora Peyvandi,