Electrochemical polymerized 5-amino-2-mercapto-1,3,4-thiadiazole modified single use sensors for detection of quercetin

In this study, electrochemical polymerized 5-amino-2-mercapto-1,3,4-thiadiazole (poly-AMT)-modified single-use graphite electrodes were fabricated for electrochemical monitoring of bisflavonoid, quercetin. The surfaces of p-AMT modified pencil graphite electrodes (PGEs) were firstly characterized by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS) analysis. The conditions for electrochemical polymerization by using cyclic voltammetry (CV), such as scan rate and different potential cycles were optimized. Electrochemical behaviors of these electrodes were also investigated using differential pulse voltammetry (DPV) and EIS. A six-fold increase at quercetin signal was obtained by using p-AMT modified PGEs compared to unmodified electrodes.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Disposable pencil graphite electrode was modified with electrochemically polymerized AMT (poly-AMT). ► Poly-AMT modified electrodes were used for electrochemical quercetin analysis. ► Surface characterization of these sensors was performed. ► AMT modified electrodes presented six-fold increased quercetin oxidation signal. ► These electrodes successfully presented quercetin detection.