| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6003223 | Thrombosis Research | 2012 | 8 Pages |
Abstract
These data demonstrate that an inhibitory effect toward glycosylated PAI-1 is a prerequisite for efficient PAI-1 inhibition in mice. Our data also suggest that PAI-1 inhibitors for use in humans must preferably be screened on glycosylated PAI-1 and not on recombinant non-glycosylated PAI-1.
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Authors
Britt Van De Craen, Ilse Scroyen, Christine Vranckx, Griet Compernolle, H. Roger Lijnen, Paul J. Declerck, Ann Gils,