Article ID Journal Published Year Pages File Type
6005061 Basal Ganglia 2012 6 Pages PDF
Abstract
Our data question a cell-intrinsic pathophysiological role of LRRK2 in Substantia nigra pars compacta dopamine neurons, but might indicate a role of LRRK2 in retrograde deterioration of dopamine neurons coming out of their projection area.
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Life Sciences Neuroscience Neurology
Preview
Reduced LRRK2-positive neurons in the striatum of Parkinson's disease patients hypothesize a retrograde disease mechanism?
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