The latency distribution of motor evoked potentials in patients with multiple sclerosis

► Individual latency distributions of motor evoked potentials allow for the assessment of slower parts of the central motor pathway. ► Using a novel method to measure alterations in these latency distributions, this study shows that in patients with multiple sclerosis, the distributions are wider than in healthy subjects. ► In patients with multiple sclerosis, slow conducting portions of the central motor pathway contribute more to the motor evoked potential.