Article ID Journal Published Year Pages File Type
600876 Colloids and Surfaces B: Biointerfaces 2012 5 Pages PDF
Abstract

This communication describes the fabrication of microstructured biopolymer surfaces by the site-selective capture of pectin hydrogel beads. A positively charged surface consisting of poly-l-lysine (PLL) was subjected to site-selective enzymatic degradation using patterned polydimethylsiloxane (PDMS) stamps covalently modified with trypsin, according to the recently described method [1]. The patterned surface was used to capture ionically cross-linked pectin beads. The desired patterning of the hydrogel surfaces was generated by site-selective immobilization of these pectin beads. The ability of the hydrogels to be dried and swollen in water was assessed.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► We describe the fabrication of microstructured surfaces by the site-selective capture of hydrogel beads. ► A surface of poly-l-lysine (PLL) was patterned to site-selective enzymatic degradation. ► The patterned surface was used to capture ionically cross-linked pectin beads. ► The ability of the hydrogels to be dried and swollen in water was assessed.

Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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