Altered face inversion effect and association between face N170 reduction and social dysfunction in patients with schizophrenia

► Normal controls showed a significant increase in N170 amplitude to inverted faces compared to upright faces while schizophrenic patients showed no such findings, whereas both groups showed no significant differences in N170 amplitude evoked by inverted and upright motor cars. ► There was a significant association between social dysfunction and face-N170 reduction in schizophrenia. ► This study revealed the association between deficits of face-specific configuration processing and social dysfunction in schizophrenia.