Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6009695 | eNeurologicalSci | 2017 | 8 Pages |
Abstract
High initial IL-6 values seem to reflect the intensity of the inflammatory response but not the brain damage per se. An early inflammatory response might even be beneficial since although elevated IL-6 levels were observed in patients with a more severe initial clinical presentation, they were not associated with neurological outcome. The lack of correlation between IL-6 and HMGB1 questions the role of macrophages in the process of the secretion of these inflammatory markers after aSAH, instead pointing to the activation of alternative pro-inflammatory pathways.
Keywords
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Authors
Heikki Kiiski, Jaakko LÃ¥ngsjö, Jyrki Tenhunen, Marika Ala-Peijari, Heini Huhtala, Mari Hämäläinen, Eeva Moilanen, Juha Ãhman, Jukka Peltola,