Autism spectrum disorder phenotype and intellectual disability in females with epilepsy and PCDH-19 mutations

Article ID	Journal	Published Year	Pages	File Type
6009879	Epilepsy & Behavior	2016	6 Pages	PDF

Abstract

Our results show a large spectrum of ID and a very high rate of ASD in patients with epilepsy and PCDH-19 mutations. Autism spectrum disorder seems to be a genuine comorbidity, more than a consequence of ID. It highlights the importance of standardized psychiatric and cognitive evaluation in order to establish a tailored rehabilitation program.

Keywords

Vineland Adaptive Behavior Scales WISC DSM WPPSI PEP ADI-R AED CBCL PDD pervasive developmental disorder Autism spectrum disorder standard deviation Epilepsy antiepileptic drug ICD Diagnostic and Statistical Manual VABS Dravet syndrome International Classification of Diseases CARS BRIEF Childhood Autism Rating Scale Wechsler Intelligence Scale for Children intellectual disability Developmental outcome ASD ADOS NEPSY Comorbidity Wechsler Preschool and Primary Scale of Intelligence Child Behavior Checklist Children