Article ID Journal Published Year Pages File Type
601097 Colloids and Surfaces B: Biointerfaces 2011 6 Pages PDF
Abstract
► Computer simulations have indicated that drugs partition and accumulate heterogeneously in the membrane. ► Their local concentrations may be much higher than in the bulk aqueous phase or even in the other regions in the lipid bilayer. ► The value of the Cloud Point (CP) depends on the structure of the amphiphile, the presence of additives, and the concentration of the amphiphile. ► It is, therefore, essential to have knowledge of clouding behavior of amphiphilic drugs under varying conditions.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
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