Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
601097 | Colloids and Surfaces B: Biointerfaces | 2011 | 6 Pages |
Abstract
⺠Computer simulations have indicated that drugs partition and accumulate heterogeneously in the membrane. ⺠Their local concentrations may be much higher than in the bulk aqueous phase or even in the other regions in the lipid bilayer. ⺠The value of the Cloud Point (CP) depends on the structure of the amphiphile, the presence of additives, and the concentration of the amphiphile. ⺠It is, therefore, essential to have knowledge of clouding behavior of amphiphilic drugs under varying conditions.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Andleeb Z. Naqvi, Suraiya Khatoon, Kabir-ud-Din Kabir-ud-Din,