Gastroesophageal reflux disease vs. Panayiotopoulos syndrome: An underestimated misdiagnosis in pediatric age?

In conclusion, we would emphasize the need to make a differential diagnosis between gastroesophageal reflux disease and Panayiotopoulos syndrome in patients with “an unusual” late-onset picture of GERD and acid therapy-resistant gastroesophageal reflux, especially if associated with other autonomic symptoms and signs.