Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
601247 | Colloids and Surfaces B: Biointerfaces | 2011 | 7 Pages |
Abstract
⺠Hybrid nanoparticles fail to form when oppositely charged lipid and drug are used. ⺠Hybrids are larger and have higher drug loading compared to non-hybrids. ⺠Drug loading of hybrids are influenced by antibiotic solubility and lipophilicity. ⺠In vitro release of hybrids are governed by the lipophilicity of the antibiotic. ⺠Hybrid nanoparticles are stable in buffer solutions only when TPGS is included.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Wean Sin Cheow, Kunn Hadinoto,