Article ID Journal Published Year Pages File Type
6013158 Epilepsy & Behavior 2013 8 Pages PDF
Abstract
► Oral gabapentin pretreatment suppressed PTZ-induced seizures in adult zebrafish. ► The anticonvulsant effects were significant and dose-dependent. ► Novel oral delivery method in adult zebrafish ascertaining accurate dose in mg/kg ► 1st report to study both behavior and cephalic field potential in one study ► This provides a novel framework for evaluating modulators of epilepsy in zebrafish.
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Life Sciences Neuroscience Behavioral Neuroscience
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