Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6013615 | Epilepsy & Behavior | 2012 | 9 Pages |
Abstract
⺠Anticonvulsant activity of sesquiterpenoids from turmeric oil in zebrafish model. ⺠Confirmation of the positive activity of bisabolene sesquiterpenoids in rodent model. ⺠Ar-turmerone and α,β-turmerone as potential AED candidates to be further investigated.
Keywords
p.o.Ar-turmeroneddH2OMTCs.c.i.v.AEDsTLEi.p.DADRP-HPLCPTZESI-MSDPFDMSOLC–MSdouble-distilled waterElectrospray Ionization Mass Spectrometrydiode array detectionMaximal electroshock seizureintraperitonealIntravenousantiepileptic drugsDimethyl sulfoxidedays post-fertilizationTurmericsubcutaneoustemporal lobe epilepsyliquid chromatography–mass spectroscopyMeSCurcuma longaTurmeric oilpolyethylene glycolPEGPentylenetetrazolereverse phase-high performance liquid chromatography
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Authors
Adriana Monserrath Orellana-Paucar, Ann-Sophie K. Serruys, Tatiana Afrikanova, Jan Maes, Wim De Borggraeve, Jo Alen, Fabián León-Tamariz, Isabel MarÃa Wilches-Arizábala, Alexander D. Crawford, Peter A.M. de Witte, Camila V. Esguerra,