Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6014315 | Epilepsy & Behavior | 2011 | 8 Pages |
Abstract
⺠Anticonvulsant activity of hydroalcoholic extract of Zizyphus jujuba was evaluated in experimental models of seizures. ⺠Extract exhibited significant dose-dependent protection against PTZ-induced seizures, with 100% protection at 1000 mg/kg. ⺠The extract exhibited a protection of 66.7% against maximal electric shock-induced seizures at 1000 mg/kg. ⺠Pretreatment with the extract significantly improved memory. ⺠The extract also reversed the seizure induced increased oxidative stress.
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Authors
Monika Pahuja, Jogender Mehla, K.H. Reeta, Sujata Joshi, Yogendra Kumar Gupta,