Article ID Journal Published Year Pages File Type
6014315 Epilepsy & Behavior 2011 8 Pages PDF
Abstract
► Anticonvulsant activity of hydroalcoholic extract of Zizyphus jujuba was evaluated in experimental models of seizures. ► Extract exhibited significant dose-dependent protection against PTZ-induced seizures, with 100% protection at 1000 mg/kg. ► The extract exhibited a protection of 66.7% against maximal electric shock-induced seizures at 1000 mg/kg. ► Pretreatment with the extract significantly improved memory. ► The extract also reversed the seizure induced increased oxidative stress.
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