“MRI-negative PET-positive” temporal lobe epilepsy: Invasive EEG findings, histopathology, and postoperative outcomes

► Invasive EEG findings, histopathology, and postoperative outcomes in patients with MRI-negative, PET-positive temporal lobe epilepsy were analyzed. ► Invasive EEG revealed that the temporal pole and hippocampus were involved most frequently in the seizure onset zone. ► At the final follow-up, 70.6% of patients were classified as Engel I. ► Histopathological evaluation showed no structural pathology in any resected hippocampus and in 58% of all evaluated temporal poles. ► The most common pathology of the temporal pole was focal cortical dysplasia type I.