Surgical resection of hypothalamic hamartomas for severe behavioral symptoms

► Patients with hypothalamic hamartoma frequently have severe psychiatric comorbidity. ► Surgical outcomes for epilepsy suggest that psychiatric comorbidity responds favorably. ► Results of HH resection in four children with surgery for behavioral indications are reported. ► Psychiatric symptoms improved in all four cases. ► Postoperative neuropsychological testing demonstrated stable or improved scores.