Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6015227 | Epilepsy Research | 2015 | 8 Pages |
Abstract
Beyond the known interactions between perampanel and EIAEDs, perampanel efficacy appears to be unaffected by the use of concomitant non-EIAED SCBs, but may be reduced in the presence of multiple concomitant AEDs (possibly indicative of the presence of more refractory epilepsy). Nonetheless, with careful titration to balance efficacy and tolerability, perampanel may be combined with a range of AEDs, facilitating integration into treatment plans.
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Authors
Patrick Kwan, Martin J. Brodie, Antonio Laurenza, Hannah FitzGibbon, Barry E. Gidal,