Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6015570 | Epilepsy Research | 2014 | 9 Pages |
Abstract
We can conclude that 6Â Hz kindling may be more advantageous than the previously described 50/60Â Hz corneal kindling models due to its robustness and persistence of the fully kindled state. Furthermore, the observed low potency and limited efficacy of AEDs in 6Â Hz fully kindled mice suggest that this model could be a useful tool in the discovery of novel AEDs targeting treatment resistant epilepsy.
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Authors
K. Leclercq, A. Matagne, R.M. Kaminski,