Article ID Journal Published Year Pages File Type
6016286 Epilepsy Research 2009 7 Pages PDF
Abstract
In conclusion, the NF-κB inhibitor and antioxidant PDTC protected the piriform cortex, whereas it did not affect hilar neuronal loss. These data might indicate that the generation of reactive oxygen species and activation of NF-κB plays a more central role in seizure-associated neuronal damage in the temporal cortex as compared to the hippocampal hilus. However, future investigations are necessary to exactly analyze the biochemical mechanisms by which PDTC exerted its beneficial effects in the piriform cortex.
Related Topics
Life Sciences Neuroscience Neurology
Authors
, , , , ,