| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6017880 | Experimental Neurology | 2014 | 13 Pages |
Abstract
Minocycline protects white matter development against oxygen toxicity through direct protection of oligodendroglia and by microglial inhibition. This study moreover demonstrates long term benefits of minocycline on white matter integrity.
Keywords
MHC IIoligodendrocyte transcription factor 2Corpus callosumSOX10PFAOPCiNOSOlig2WMDTNFMajor histocompatibility class IINGSROIMBPinducible NO synthaseWhite matter damageMRIinterferonIFNinterleukinMagnet resonance imagingTUNELnormal goat serumtumor necrosis factormicroglial activationwhite matterNeuroprotectionimmature brainregion of interestMinocyclinefractional anisotropypreterm infantsHypomyelinationHyperoxiaparaformaldehydeMyelin basic proteinexternal capsule
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Authors
Thomas Schmitz, Grietje Krabbe, Georg Weikert, Till Scheuer, Friederike Matheus, Yan Wang, Susanne Mueller, Helmut Kettenmann, Vitali Matyash, Christoph Bührer, Stefanie Endesfelder,