| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6017923 | Experimental Neurology | 2013 | 11 Pages |
Abstract
Our results indicate that WOKW rats show an up-regulated autophagy and a mild inflammatory response but do not develop overt neuropathy. We suggest that autophagy and inflammatory cells may exert a protective role in preventing neuropathy in this rat model of the metabolic syndrome but the mechanism of action is still unclear.
Keywords
FITCcluster of differentiation 3autophagy protein 5Unmyelinated fiberATG5cd3IENFDPGP9.5HbA1cATG7CMAPCy3LC3Gap43neurofilament 200GAPDHNCVNF200d-glyceraldehyde-3-phosphate dehydrogenaseIba-1AutophagyEpidermisIntraepidermal nerve fiber densityCluster of differentiation 68DermisCNSgrowth associated protein 43nerve conduction velocitySchwann cellMetabolic syndromeCyanine 3central nervous systemperipheral nervous systemSNAPSciatic nervefluorescein isothiocyanateMyelinated fiberionized calcium binding adapter molecule 1Sensory nerve action potentialcompound muscle action potentialMyelin protein zeroperipheral neuropathyprotein gene product 9.5PNS
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
J. Kosacka, M. Nowicki, M. Blüher, P. Baum, M. Stockinger, K.V. Toyka, I. Klöting, M. Stumvoll, H. Serke, I. Bechmann, N. Klöting,